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Assignment代写:紫杉醇PEG-PLGA共聚物纳米粒

表示,使用个人药物化疗已经显示出一定的抗肿瘤治疗的局限性。当结合药物,它导致了更好的性能。在本文中,作者提出减少每种药物的数量。这样做是为了获得协同的效果自然疗法的癌症。各种研究人员试图与化疗药物以同步的方式通过使用运营商的药物如脂质体、胶束和无机纳米粒子的性质。本文报告与核壳纳米粒子在双乳化方式从共聚物具有两亲性质。他们使用的丙烯甲氧基聚(乙二醇)聚(lactide-co-glycolide)。

Assignment代写:紫杉醇PEG-PLGA共聚物纳米粒

这些纳米粒子导致提供的好处在相关nano-carriers因为他们容易制造的能力。这是通过双乳液称为生物相容性的简易方法。加载显示更高的功效。更重要的是,这些纳米粒子的能力co-delivering阿霉素的亲水疏水性质的性质以及紫杉醇。纳米粒子含有药物,有很好的多分散的能力。这个描述,他们更容易受到控制的分布大小。药物释放的研究以及co-delivery系统描述细胞吸收,药物通过细胞,同时有效地释放。

Assignment代写:紫杉醇PEG-PLGA共聚物纳米粒

stated that using individual drug for chemotherapy has shown certain anti-tumor treatment limitations. When combining the drugs, it results in better performance. In this article, the authors proposed minimizing each drug’s amount. This was done to gain the effect of synergistic nature for therapies of cancer . Various researchers have attempted to deliver drugs with chemotherapeutics in a simultaneous manner through use of carriers of drugs such as liposomes, micelles and nano-particles of inorganic nature. The article reported Nano particles with core shells to be emulsified in a double manner from copolymers having amphiphilic nature. The co-polymer used by them was methoxy poly (ethylene glycol)-poly (lactide-co-glycolide).

Assignment代写:紫杉醇PEG-PLGA共聚物纳米粒

Such nano-particles resulted in offering benefits over related nano-carriers because they had the ability of easy fabrication. This was done through improvised method for double emulsion known as biocompatibility . It showed higher efficacy for loading. More significantly, these nano-particles had the ability of co-delivering doxorubicin of hydrophilic nature as well as paclitaxel of hydrophobic nature. The nano-particles loaded with drug, had good ability to polydisperse. This depicted that they were subjected more readily to controlled distribution of size. Drug release studies as well as co-delivery systems cellular uptake depicted that the drugs were taken up effectively through cells and simultaneously released.