There have been cases where people have died due to fatigue and dehydration leading to heart failure. In 2010, US swimmer Fran Crippen died due to this factor. The air temperature was very high that day and on top of the heat, the temperature of the water was very high too. Severe fatigue led to his death as per the reports, but, the root cause of this fatgue was the heat (Fantz, 2010).
The couple had very high alcohol content in their blood and was quite drunk at the time of their death. Wine causes a huge amount of dehydration (Gordis, 2008). If not treated, there may be delirium, unconsciousness and, in extreme cases, death. Symptoms of dehydration are noticeable after losing just 2 percent of the volume of water. Initially thirst and discomfort appear, possibly accompanied by loss of appetite and dry skin. Athletes may suffer a loss that increases problems by 30 percent. It leads to loss of strength, increased heart rate, increased body temperature, and fatigue. Symptoms become increasingly severe with greater water loss. Heart rate and respiratory rate begin to rise the decline in the volume of blood plasma and blood pressure to offset. In turn, the body temperature may increase due to decreased sweating. Having lost about 5 or 6 percent water, an individual can get sleepy, may have headaches, nausea and tingling in the limbs. If a person loses 10 to 15 percent of body water, the muscles become spastic, skin becomes dry and wrinkle, vision becomes cloudy, urine volume is considerably reduced. Over 15 percent loss is usually fatal (Sarda, 2008).
有一些人死于疲劳和脱水导致心脏衰竭。2010，美国游泳运动员弗兰Crippen死于这一因素。空气的温度是很高的那一天，在顶部的热，水的温度是非常高的太。严重的疲劳导致了他的死亡，根据报道，但是，这种疲劳的根本原因是热（范茨，2010）。
这对夫妇有很高的酒精含量在他们的血液和喝醉了在他们的死亡时间。酒导致脱水大量（戈迪斯，2008）。如果不治疗，可能有谵妄，意识不清和，在极端的情况下，死亡。仅仅损失百分之2的水的体积后脱水症状是明显的。最初的渴望和不适出现，可能伴有食欲不振、皮肤干燥。运动员可能会遭受损失，增加的问题百分之30。它导致的强度损失，增加心率，体温升高，疲劳。症状越来越严重的更大的水的损失。心率和呼吸率开始上升，血浆和血液的压力偏移量的下降。反过来，身体的温度会增加由于减少出汗。失去了约5或百分之6的水，一个人可以被困，可能有头痛，恶心，四肢刺痛。如果一个人失去了10到百分之15的水，变成肌肉痉挛，皮肤变得干燥起皱，视觉变得浑浊，尿量显著减少。超过百分之15的损失通常是致命的（戒毒，2008）。
