In the year 1954 the micro technology was invented. After this the engineers felt the need to understand the structure of the electronic chips that were used in various instruments. With the discovery of compatible tools there also arise the needs of developing a technology which is compatible in size but still can perform tasks of large machines. Again the invention of various sensors like fluid sensors, airbag sensors and pressure sensors created more necessity of the microelectronic chips. And thus from 1966 the era of microelectronic chips began. The first successful lab on chip was developed in the year 1975 and was used in a Gas Chromatography. It was designed by a Professor at Stanford University known as S.C. Terry (Srinivasan, 2004). But till this period not much people were taking interest in the lab on chip. The main research and development of lab on chip was begun in 1990’s especially in Europe where the chips were used in pumps and fluid treatment systems. The lab on chip showed that the in the Fluid treatment systems those procedures like cleaning and separation that were earlier being done at a lab scale, with the integration of the microelectronic chips can be done at the production scale. This reduced lot of time and efforts. Lab on chip became popular in 1990 when they were started being used in various biotechnologically interesting tools like for DNA Micro Arrays, Genomics Applications and Capillary electrophoresis. Another biggest development that was seen was when the military units like Defence Advanced Research Projects Agency started researching on the chip in order to use it for analysis of any kind of biological or chemical weapons those were used in wars (Paik, 2003). Today major industries like software, communications, defence etc functions on the applications of lab on chip and so more and more research are being carried out in this field.
在1954年度的显微技术被发明。这之后，工程师需要了解被用于在各种仪器的电子芯片的结构。有兼容的工具的发现也出现发展是兼容的大小，但仍然可以执行任务的需要，大型机技术。再次对各种传感器流体传感器的发明，气囊传感器和压力传感器制造更多的微电子芯片的必要性。因此，从1966微电子芯片时代的开始。芯片上的第一个成功的实验室在1975年的发展，进行了气相色谱法。这是在斯坦福大学被称为SC特里教授设计（Srinivasan，2004）。但直到这段时间不多的人在实验室中对芯片的兴趣。芯片上的实验室的主要研究和发展是1990年代开始在欧洲特别是在芯片中使用的泵和流体处理系统。芯片上的实验室发现，在流体处理系统的程序，如清洗和分离，早在一个实验室规模的完成，随着微电子芯片的集成可以在生产规模。这减少了大量的时间和努力。芯片实验室成为流行在1990当他们开始使用各种生物技术有趣的工具，如DNA微阵列的基因组学中的应用，以及毛细管电泳。另一个最大的发展，被认为是当军事单位像国防高级研究项目署开始研究为了在芯片上，使用它为任何一种生物或化学武器进行战争（p，2003）。今天主要的行业软件，通信，国防等功能在芯片实验室中的应用，越来越多的研究正在进行这方面的。
